Entry Detail


General Information

Database ID:exR0514733
RNA Name:ENSA
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):150600851End Site(bp):150629612
External Links:ENSG00000143420



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006030.1
chr2
74211604
74363377
-
AC007192.1
chr19
18153158
18178117
+
AC139530.2
chr17
81703371
81720539
+
ACP1
chr2
264140
278283
+
ACVR1B
chr12
51951699
51997078
+
ADAR
chr1
154582057
154628013
-
AFF4
chr5
132875395
132963634
-
AIF1L
chr9
131096476
131123152
+
AL365205.1
chr6
41780349
41790141
+
ALDH3A2
chr17
19648136
19685760
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-28-5p
chr3
188688794
188688815
+
hsa-miR-338-3p
chr17
81125887
81125908
-
hsa-miR-708-5p
chr11
79402077
79402099
-
hsa-miR-1224-5p
chr3
184241405
184241423
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009055.2
chr16
65190973
65234914
-
AC091564.7
chr11
6610883
6616594
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.