Entry Detail


General Information

Database ID:exR0514868
RNA Name:EWSR1
RNA Type:mRNA
Chromosome:chr22
Starnd:+
Coordinate:
Start Site(bp):29268009End Site(bp):29300525
External Links:ENSG00000182944



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCA1
chr9
104781006
104928155
-
ABCE1
chr4
145098288
145129524
+
ABHD4
chr14
22598237
22613215
+
AC010422.3
chr19
12643831
12648397
-
AC026954.2
chr17
7312661
7319174
-
AC120057.2
chr17
7240427
7244635
-
ACD
chr16
67657512
67660815
-
ACSL4
chrX
109624244
109733403
-
ACTG1
chr17
81509971
81523847
-
ACTR1B
chr2
97655939
97664044
-
ACVR1
chr2
157736444
157876330
-
ADH5
chr4
99070978
99088801
-
AHCYL1
chr1
109984765
110023742
+
AIP
chr11
67483026
67491103
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-6777-5p
chr17
17813518
17813540
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.