Entry Detail


General Information

Database ID:exR0515108
RNA Name:FASN
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):82078338End Site(bp):82098294
External Links:ENSG00000169710



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
A3GALT2
chr1
33306766
33321098
-
AASS
chr7
122073549
122144255
-
ABCA2
chr9
137007234
137028922
-
ABHD8
chr19
17292131
17310236
-
ABTB2
chr11
34150987
34358010
-
AC011448.1
chr19
19516227
19536076
+
AC023055.1
chr12
55757275
55827546
-
AC026954.2
chr17
7312661
7319174
-
AC068580.4
chr11
1734821
1763954
-
AC107871.1
chr15
68184032
68229718
-
ACAD9
chr3
128879596
128916067
+
ADAMTS1
chr21
26835755
26845409
-
ADCK1
chr14
77800109
77935014
+
ADGRG2
chrX
18989307
19122637
-
AFG3L2
chr18
12328944
12377227
-
AGAP4
chr10
45825594
45853875
-
AGBL5
chr2
27042364
27070622
+
AGPAT4
chr6
161129967
161274061
-
AGRN
chr1
1020120
1056118
+
AKAP12
chr6
151239967
151358559
+
AKIRIN2
chr6
87674860
87702233
-
AKT1
chr14
104769349
104795751
-
AL021546.1
chr12
120438198
120460006
+
AL133352.1
chr10
100505628
100529881
-
AL139011.2
chr1
160216800
160285130
-
ALDH16A1
chr19
49453225
49471050
+
ALDH9A1
chr1
165662216
165698863
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-29a-3p
chr7
130876748
130876769
-
hsa-miR-29b-3p
chr7
130877467
130877489
-
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-107
chr10
89592756
89592778
-
hsa-miR-29c-3p
chr1
207801865
207801886
-
hsa-miR-526b-5p
chr19
53694406
53694428
+
hsa-miR-652-3p
chrX
110055389
110055409
+
hsa-miR-663a
chr20
26208243
26208264
-
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-147b-3p
chr15
45433098
45433118
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006538.1
chr19
2727743
2729327
-
AC016876.2
chr17
7581964
7584086
-
AC019205.1
chr6
73263212
73301789
+
AC023509.1
chr12
53441741
53467528
+
AC103702.2
chr17
48635923
48647023
-
AC106864.1
chr4
112693047
112706810
-
AC124068.2
chr15
89335053
89336161
+
AD000090.1
chr19
35557956
35581954
+
AL021707.3
chr22
38734730
38738990
+
AL121992.1
chr1
15586136
15603626
-
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.