Entry Detail


General Information

Database ID:exR0515140
RNA Name:FBXL19
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):30923055End Site(bp):30948783
External Links:ENSG00000099364



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCA2
chr9
137007234
137028922
-
ABL2
chr1
179099330
179229684
-
ABRACL
chr6
139028745
139043302
+
AC018523.2
chr11
14493783
14520344
-
AC233992.2
chr8
144353228
144355609
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADAMTS19
chr5
129460281
129738683
+
ADRM1
chr20
62302093
62308862
+
AFF3
chr2
99545419
100192428
-
AGO3
chr1
35930718
36072500
+
AGRN
chr1
1020120
1056118
+
AL031708.1
chr16
1632259
1686715
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-22-3p
chr17
1713914
1713935
-
hsa-miR-324-3p
chr17
7223308
7223330
-
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-423-5p
chr17
30117095
30117117
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC125807.2
chr12
3041437
3044950
+
AC135048.1
chr16
30948386
30956511
+
AC245014.3
chr1
145281116
145281462
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.