Entry Detail


General Information

Database ID:exR0717427
RNA Name:NPM1
RNA Type:mRNA
Chromosome:chr5
Starnd:+
Coordinate:
Start Site(bp):171387116End Site(bp):171411137
External Links:ENSG00000181163



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC073508.2
chr17
40627356
40665141
-
AL121594.1
chr14
35122549
35317474
+
AC092143.1
chr16
89919165
89936092
+
AC007192.1
chr19
18153158
18178117
+
ACTB
chr7
5527148
5563784
-
ADH5
chr4
99070978
99088801
-
AC138969.1
chr16
16317444
16350590
+
ABCC1
chr16
15949577
16143074
+
AC008982.1
chr19
38817471
38840178
-
AC004922.1
chr7
99325879
99394653
+
AL365205.1
chr6
41780349
41790141
+
ADD1
chr4
2843857
2930076
+
AC126283.2
chr4
109713916
109801999
-
AC005258.1
chr19
2269525
2341172
+
AL031708.1
chr16
1632259
1686715
+
AL139011.2
chr1
160216800
160285130
-
ADAM23
chr2
206443532
206621127
+
ABT1
chr6
26596953
26600739
+
ALDH2
chr12
111766887
111817532
+
AGPAT5
chr8
6708642
6761503
+
ADGRG6
chr6
142301854
142446266
+
AC120057.2
chr17
7240427
7244635
-
ACTG1
chr17
81509971
81523847
-
AHCYL1
chr1
109984765
110023742
+
AACS
chr12
125065434
125143333
+
ADGRD1
chr12
130953907
131141469
+
ALDH18A1
chr10
95605941
95656711
-
ALDH3A2
chr17
19648136
19685760
+
ACTR1A
chr10
102461881
102502712
-
AC010463.1
chr19
17267418
17282966
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-92a-3p
chrX
134169544
134169565
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007218.1
chr16
9666885
9676843
-
AC007952.4
chr17
19112000
19112636
-
AC011498.1
chr19
4457962
4471493
-
AC022140.1
chr5
25404733
25445925
-
AD000090.1
chr19
35557956
35581954
+
AL021707.1
chr22
38739003
38749041
+
AL137003.1
chr6
16764346
16766883
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.