Entry Detail


General Information

Database ID:exR0717591
RNA Name:NUP62
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):49906825End Site(bp):49929763
External Links:ENSG00000213024



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABRACL
chr6
139028745
139043302
+
AC007192.1
chr19
18153158
18178117
+
AC010422.3
chr19
12643831
12648397
-
AC011462.1
chr19
41350853
41425001
+
AC068946.2
chr2
219209772
219222738
-
AC138696.1
chr8
143247110
143276403
+
ACAA2
chr18
49782164
49813953
-
ACACA
chr17
37084992
37406836
-
ACADVL
chr17
7217125
7225266
+
ACAP3
chr1
1292390
1309609
-
ACIN1
chr14
23058564
23095614
-
ACSF3
chr16
89088375
89164121
+
ACTB
chr7
5527148
5563784
-
ADGRE5
chr19
14380501
14408725
+
ADGRL1
chr19
14147743
14206187
-
AFF2
chrX
148500617
149000663
+
AGAP3
chr7
151085831
151144436
+
AGO3
chr1
35930718
36072500
+
AKAP8L
chr19
15380050
15419141
-
AKT2
chr19
40230317
40285536
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC004812.2
chr12
120116907
120119000
+
AC073957.2
chr7
1055360
1059261
-
AC091271.1
chr17
59618553
59619714
-
AF131216.3
chr8
11345748
11347502
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.