Entry Detail


General Information

Database ID:exR0717624
RNA Name:OAZ1
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):2269509End Site(bp):2273490
External Links:ENSG00000104904



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAGAB
chr15
67200667
67255195
-
ABCB8
chr7
151028422
151047782
+
ABL2
chr1
179099330
179229684
-
AC005258.1
chr19
2269525
2341172
+
AC006030.1
chr2
74211604
74363377
-
AC008982.1
chr19
38817471
38840178
-
AC010422.3
chr19
12643831
12648397
-
AC011455.2
chr19
38915404
38949855
-
AC073508.2
chr17
40627356
40665141
-
AC104109.3
chr5
134167170
134226071
-
AC124312.1
chr15
24955034
25000276
+
ACAT2
chr6
159762045
159779112
+
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTL6A
chr3
179562886
179588407
+
ACTN1
chr14
68874143
68979440
-
ACTR8
chr3
53867066
53882152
-
ADAR
chr1
154582057
154628013
-
AEN
chr15
88621337
88632281
+
AHCTF1
chr1
246839098
246931967
-
AHSA1
chr14
77457870
77469472
+
AIFM1
chrX
130129362
130165887
-
AKAP1
chr17
57085092
57121346
+
AL133352.1
chr10
100505628
100529881
-
AL139260.3
chr1
38864501
38881617
-
ALCAM
chr3
105366909
105576900
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC009908.1
chr8
124996985
124998198
-
AC067930.1
chr8
143579636
143580670
+
AC079145.1
chr2
19990209
20004795
+
AC087392.5
chr17
795306
795794
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.