Entry Detail


General Information

Database ID:exR0718058
RNA Name:P4HB
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):81843161End Site(bp):81860624
External Links:ENSG00000185624



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCB7
chrX
75051048
75156732
-
ABCF2
chr7
151207837
151227166
-
ABLIM1
chr10
114431113
114768061
-
ABR
chr17
1003518
1229738
-
AC010132.3
chr7
42909273
42932174
-
AC015813.2
chr17
57989038
58007246
-
AC087289.3
chr17
75898645
75930129
-
ACAD11
chr3
132558138
132660082
-
ACLY
chr17
41866917
41930542
-
ACOT9
chrX
23701055
23766475
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR3
chr2
113890063
113962596
+
ADD2
chr2
70607618
70768225
-
ADORA2A
chr22
24417879
24442357
+
ADPRHL2
chr1
36088892
36093932
+
ADSL
chr22
40346500
40390463
+
AGRN
chr1
1020120
1056118
+
AHCY
chr20
34280268
34311802
-
AK2
chr1
33007940
33080996
-
AKR1B1
chr7
134442356
134459284
-
AKT1
chr14
104769349
104795751
-
AL022238.4
chr22
40346529
40410054
+
AL121758.1
chr20
646626
675800
-
AL590764.2
chrX
71103987
71111575
-
ALDH1B1
chr9
38392702
38398661
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC055860.1
chr11
18000542
18022931
-
AC060780.1
chr17
43148368
43171037
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.