Entry Detail


General Information

Database ID:exR0718141
RNA Name:PARP1
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):226360691End Site(bp):226408093
External Links:ENSG00000143799



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD14B
chr3
51968510
51983409
-
ABL1
chr9
130713016
130887675
+
ABRACL
chr6
139028745
139043302
+
ABTB1
chr3
127672935
127680926
+
AC010323.1
chr19
8308283
8321379
-
AC010422.3
chr19
12643831
12648397
-
AC011462.1
chr19
41350853
41425001
+
AC027796.3
chr17
3585149
3636249
-
AC048338.1
chr12
122207779
122266423
-
AC245033.1
chr15
82536788
82573194
-
ACOT13
chr6
24667035
24705065
+
ACSF2
chr17
50426158
50474845
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADGRA3
chr4
22345071
22516066
-
ADH5
chr4
99070978
99088801
-
ADRM1
chr20
62302093
62308862
+
AGL
chr1
99850361
99924023
+
AL117348.2
chr1
225886696
225924278
-
AL162417.1
chr9
133098121
133163914
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-155-5p
chr21
25573983
25574006
+
hsa-miR-496
chr14
101060628
101060649
+
hsa-miR-556-3p
chr1
162342600
162342621
+
hsa-miR-4700-3p
chr12
120723233
120723258
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009831.1
chr18
31942575
31944156
+
AC106864.1
chr4
112693047
112706810
-
AC132217.1
chr11
2129121
2129964
-
AC245014.3
chr1
145281116
145281462
+
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.