Entry Detail


General Information

Database ID:exR0718185
RNA Name:PCBP1
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):70087477End Site(bp):70089203
External Links:ENSG00000169564



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
ABL1
chr9
130713016
130887675
+
AC011448.1
chr19
19516227
19536076
+
AC104581.2
chr17
7925931
7930622
-
AC114490.2
chr1
34981533
35031741
-
AC245033.1
chr15
82536788
82573194
-
ACOT9
chrX
23701055
23766475
-
ACOX3
chr4
8366282
8440723
-
ACP1
chr2
264140
278283
+
ACTG1
chr17
81509971
81523847
-
ACTR1B
chr2
97655939
97664044
-
ACVR2B
chr3
38453890
38493142
+
ADRA2C
chr4
3766348
3768526
+
AHSA1
chr14
77457870
77469472
+
AJM1
chr9
136844415
136848801
+
AL132780.3
chr14
22946270
22982258
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC011825.3
chr18
32018829
32111779
+
AC020928.2
chr19
36773712
36775908
-
AC023509.1
chr12
53441741
53467528
+
AC087190.3
chr16
9104848
9113181
+
AC091564.7
chr11
6610883
6616594
-
AL118506.1
chr20
63861212
63864293
-
AL132639.2
chr14
39265703
39267061
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.