Entry Detail


General Information

Database ID:exR0718419
RNA Name:PGAM1
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):97426191End Site(bp):97433444
External Links:ENSG00000171314



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASDHPPT
chr11
106075501
106098699
+
ABCB6
chr2
219209772
219218994
-
ABHD17C
chr15
80679684
80755621
+
ABI2
chr2
203328239
203447728
+
ABL2
chr1
179099330
179229684
-
AC007846.2
chr17
5772926
6080792
+
AC073082.1
chr2
48632291
48755724
-
AC091959.3
chr5
146203550
146339251
+
AC110275.1
chr8
43018424
43077334
+
AC139530.2
chr17
81703371
81720539
+
AC245033.1
chr15
82536788
82573194
-
ACACA
chr17
37084992
37406836
-
ACAT2
chr6
159762045
159779112
+
ACBD7
chr10
15075475
15088776
-
ACTB
chr7
5527148
5563784
-
ACTR1A
chr10
102461881
102502712
-
ACTR1B
chr2
97655939
97664044
-
ADA
chr20
44619522
44652233
-
ADAR
chr1
154582057
154628013
-
ADD2
chr2
70607618
70768225
-
AFAP1
chr4
7758714
7939926
-
AGBL5
chr2
27042364
27070622
+
AKT2
chr19
40230317
40285536
-
AL024498.2
chr6
10747794
10930423
+
AL157392.5
chr10
13610047
13655929
+
ALDH18A1
chr10
95605941
95656711
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-423-5p
chr17
30117095
30117117
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009022.1
chr16
69976297
70065948
-
AC026461.1
chr16
56682470
56687807
+
AC245033.4
chr15
82533175
82540008
-
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.