Entry Detail


General Information

Database ID:exR0718432
RNA Name:PGK1
RNA Type:mRNA
Chromosome:chrX
Starnd:+
Coordinate:
Start Site(bp):77910739End Site(bp):78129295
External Links:ENSG00000102144



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AIFM2
chr10
70098223
70132934
-
AC012254.2
chr18
47108188
47176345
-
AKIRIN2
chr6
87674860
87702233
-
AHSA1
chr14
77457870
77469472
+
AC011005.1
chr7
129126518
129130793
+
ADPGK
chr15
72751369
72785846
-
AKIRIN1
chr1
38991276
39006059
+
ABCC5
chr3
183919934
184017939
-
ABCB7
chrX
75051048
75156732
-
AFF4
chr5
132875395
132963634
-
ADCY5
chr3
123282296
123449758
-
AL121753.1
chr20
35267885
35280043
-
AC010422.5
chr19
12664828
12669397
-
AGGF1
chr5
77029251
77065234
+
ACTG1
chr17
81509971
81523847
-
ADGRB2
chr1
31727117
31764893
-
ABCE1
chr4
145098288
145129524
+
ACTR3
chr2
113890063
113962596
+
AC023055.1
chr12
55757275
55827546
-
AL355987.1
chr9
136738167
136748453
-
ADH5
chr4
99070978
99088801
-
ACAT1
chr11
108116695
108147603
+
AC008581.2
chr5
77030902
77152155
+
AFTPH
chr2
64524305
64593005
+
AAMP
chr2
218264123
218270257
-
ALDOA
chr16
30064164
30070457
+
ACTB
chr7
5527148
5563784
-
AL133352.1
chr10
100505628
100529881
-
ALDH3A2
chr17
19648136
19685760
+
AGFG1
chr2
227472152
227561214
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-29b-3p
chr7
130877467
130877489
-
hsa-miR-30c-5p
chr6
71377003
71377025
-
hsa-miR-136-5p
chr14
100884716
100884738
+
hsa-miR-299-3p
chr14
101023832
101023853
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC000068.1
chr22
19447893
19450105
+
AC007952.4
chr17
19112000
19112636
-
AC020663.1
chr16
4730115
4752565
-
AC023509.1
chr12
53441741
53467528
+
AC048341.2
chr12
62603909
62604399
+
AC074183.1
chr7
84939349
84940245
-
AC079781.5
chr7
97851688
97972985
-
AC091132.5
chr17
45549781
45558738
-
AC106864.1
chr4
112693047
112706810
-
AC113189.4
chr17
7439506
7445966
+
AC132217.1
chr11
2129121
2129964
-
AC133644.3
chr2
87455476
87767359
+
AL022311.1
chr22
37876148
37895563
+
AL137026.2
chr10
44259602
44261813
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.