Entry Detail


General Information

Database ID:exR0718779
RNA Name:PODXL
RNA Type:mRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):131500262End Site(bp):131558217
External Links:ENSG00000128567



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004922.1
chr7
99325879
99394653
+
AC005943.1
chr19
1578339
1605445
-
AC010422.3
chr19
12643831
12648397
-
AC073508.2
chr17
40627356
40665141
-
AC091167.2
chr15
90249556
90272208
+
AC118553.2
chr1
99970011
100083321
+
AC135050.2
chr16
31083439
31094956
-
ACAA2
chr18
49782164
49813953
-
ACAD8
chr11
134253495
134265855
+
ACP1
chr2
264140
278283
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR1A
chr10
102461881
102502712
-
ADCY3
chr2
24819169
24919839
-
ADD3
chr10
109996368
110135565
+
AFDN
chr6
167826922
167972023
+
AHCY
chr20
34280268
34311802
-
AIF1L
chr9
131096476
131123152
+
AKT1
chr14
104769349
104795751
-
AKT1S1
chr19
49869033
49878459
-
AL133352.1
chr10
100505628
100529881
-
AL162417.1
chr9
133098121
133163914
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-4709-5p
chr14
74480175
74480196
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.