Entry Detail


General Information

Database ID:exR0718811
RNA Name:POLR1D
RNA Type:mRNA
Chromosome:chr13
Starnd:+
Coordinate:
Start Site(bp):27620742End Site(bp):27744237
External Links:ENSG00000186184



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCC4
chr13
95019835
95301475
-
AC009133.6
chr16
29812261
29820092
+
AC011448.1
chr19
19516227
19536076
+
AC087289.3
chr17
75898645
75930129
-
AC092143.1
chr16
89919165
89936092
+
AC093155.3
chr1
86993009
87169204
+
AC124312.1
chr15
24955034
25000276
+
ACLY
chr17
41866917
41930542
-
ACOT7
chr1
6264269
6394391
-
ACSS3
chr12
80936414
81261210
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTL6A
chr3
179562886
179588407
+
ACTR1A
chr10
102461881
102502712
-
ACTR2
chr2
65227753
65271253
+
AD000671.2
chr19
35739252
35745432
-
ADSL
chr22
40346500
40390463
+
AGPAT5
chr8
6708642
6761503
+
AKT3
chr1
243488233
243851079
-
AL022238.4
chr22
40346529
40410054
+
AL365205.1
chr6
41780349
41790141
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC142472.1
chr17
45146730
45148470
-
AC244517.5
chr5
141046260
141096402
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.