Entry Detail



General Information

Database ID:exR0718869
RNA Name:POU5F1
RNA Type:mRNA
Chromosome:chr6
Starnd:-
Coordinate:
Start Site(bp):31164337End Site(bp):31180731
External Links:ENSG00000204531



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCD4
chr14
74285269
74303055
-
ABCE1
chr4
145098288
145129524
+
ABHD14A-ACY1
chr3
51974706
51989183
+
ABL1
chr9
130713016
130887675
+
AC008764.1
chr19
16479067
16628204
-
AC008982.1
chr19
38817471
38840178
-
AC018512.1
chr15
43772617
43799133
-
AC023055.1
chr12
55757275
55827546
-
AC068946.2
chr2
219209772
219222738
-
AC073508.2
chr17
40627356
40665141
-
AC124312.1
chr15
24955034
25000276
+
AC245033.1
chr15
82536788
82573194
-
ACO2
chr22
41469117
41528989
+
ACOX1
chr17
75941507
75979177
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
ACTR3B
chr7
152759749
152855378
+
ACY1
chr3
51983340
51989197
+
ADAMTS7
chr15
78759206
78811464
-
ADAR
chr1
154582057
154628013
-
AEN
chr15
88621337
88632281
+
AFDN
chr6
167826922
167972023
+
AHCY
chr20
34280268
34311802
-
AIMP2
chr7
6009255
6023834
+
AJUBA
chr14
22971177
22982551
-
AKT1
chr14
104769349
104795751
-
AL121758.1
chr20
646626
675800
-
ALAD
chr9
113386312
113401290
-
ALDH1B1
chr9
38392702
38398661
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004846.1
chr14
73242651
73245979
-
AC016876.2
chr17
7581964
7584086
-
AC020663.1
chr16
4730115
4752565
-
AC126365.1
chr17
20788071
20789584
+
AC132217.1
chr11
2129121
2129964
-
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.