Entry Detail


General Information

Database ID:exR0718893
RNA Name:PPIA
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):44796680End Site(bp):44824564
External Links:ENSG00000196262



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD10
chr3
111979010
111993368
+
ABLIM1
chr10
114431113
114768061
-
AC011005.1
chr7
129126518
129130793
+
AC011462.1
chr19
41350853
41425001
+
AC068946.1
chr2
219075329
219170827
-
ACAA2
chr18
49782164
49813953
-
ACPP
chr3
132317369
132368298
+
ACTA1
chr1
229431245
229434098
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADIPOR1
chr1
202940826
202958572
-
ADIPOR2
chr12
1688574
1788674
+
ADK
chr10
74151202
74709963
+
AFMID
chr17
78187317
78207701
+
AGL
chr1
99850361
99924023
+
AL136454.1
chr1
192716132
192716653
+
AL713999.1
chr1
155169409
155187272
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4426
chr1
192716333
192716349
+
hsa-miR-6850-5p
chr8
144791970
144791991
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC018521.1
chr17
47945424
47981736
+
AC067852.1
chr17
42536510
42562062
+
AC091729.3
chr7
1160374
1165607
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.