Entry Detail


General Information

Database ID:exR0718897
RNA Name:PPIB
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):64155812End Site(bp):64163205
External Links:ENSG00000166794



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCD4
chr14
74285269
74303055
-
ABHD14B
chr3
51968510
51983409
-
AC245033.1
chr15
82536788
82573194
-
ACER3
chr11
76860867
77026797
+
ACLY
chr17
41866917
41930542
-
ACOT1
chr14
73537143
73543796
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADA
chr20
44619522
44652233
-
ADCY9
chr16
3953387
4116442
-
ADGRG5
chr16
57542643
57591681
+
ADH5
chr4
99070978
99088801
-
AKAP12
chr6
151239967
151358559
+
ALDH7A1
chr5
126531200
126595362
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-302d-3p
chr4
112648006
112648028
-
hsa-miR-3940-5p
chr19
6416470
6416489
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC023509.1
chr12
53441741
53467528
+
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.