Entry Detail


General Information

Database ID:exR0719035
RNA Name:PRDX6
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):173477330End Site(bp):173488815
External Links:ENSG00000117592



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002985.1
chr19
18907013
18934397
-
AC011511.4
chr19
10315471
10320678
-
AC046185.1
chr17
63702845
63752097
-
AC092143.1
chr16
89919165
89936092
+
AC138969.1
chr16
16317444
16350590
+
AC139530.2
chr17
81703371
81720539
+
ACAA2
chr18
49782164
49813953
-
ACBD6
chr1
180269653
180502954
-
AFF1
chr4
86935002
87141054
+
AKIRIN1
chr1
38991276
39006059
+
AKT3
chr1
243488233
243851079
-
AL136295.5
chr14
24147548
24166452
+
AL365205.1
chr6
41780349
41790141
+
ALDH9A1
chr1
165662216
165698863
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006141.1
chr17
51249579
51251748
-
AC007406.5
chr12
273954
277123
-
AC051619.7
chr15
45200325
45200632
-
AC126365.1
chr17
20788071
20789584
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.