Entry Detail


General Information

Database ID:exR0719136
RNA Name:PRR12
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):49591182End Site(bp):49626439
External Links:ENSG00000126464



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC139530.2
chr17
81703371
81720539
+
AC245033.1
chr15
82536788
82573194
-
ACTG1
chr17
81509971
81523847
-
ADCY6
chr12
48766194
48789037
-
AGO3
chr1
35930718
36072500
+
AGPAT3
chr21
43865223
43987592
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-122-5p
chr18
58451088
58451109
+
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-206
chr6
52144401
52144422
+
hsa-miR-449a
chr5
55170586
55170607
-
hsa-miR-663a
chr20
26208243
26208264
-
hsa-miR-449b-5p
chr5
55170706
55170727
-
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-629-5p
chr15
70079427
70079447
-
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-744-5p
chr17
12081909
12081930
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020910.5
chr19
34733298
34733837
-
AC022211.2
chr17
75145261
75146546
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.