Entry Detail


General Information

Database ID:exR0719184
RNA Name:PSAP
RNA Type:mRNA
Chromosome:chr10
Starnd:-
Coordinate:
Start Site(bp):71816298End Site(bp):71851325
External Links:ENSG00000197746



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD4
chr14
22598237
22613215
+
AC008764.1
chr19
16479067
16628204
-
AC015813.2
chr17
57989038
58007246
-
AC138811.2
chr16
18788063
18801519
-
AC245033.1
chr15
82536788
82573194
-
ACAA1
chr3
38103129
38137242
-
ACD
chr16
67657512
67660815
-
ACKR3
chr2
236567787
236582354
+
ACOX1
chr17
75941507
75979177
-
ACTB
chr7
5527148
5563784
-
ACTN4
chr19
38647649
38731589
+
ADH5
chr4
99070978
99088801
-
ADI1
chr2
3497366
3519531
-
AGPAT5
chr8
6708642
6761503
+
AHSA1
chr14
77457870
77469472
+
AKT2
chr19
40230317
40285536
-
AL022238.4
chr22
40346529
40410054
+
AL136295.5
chr14
24147548
24166452
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004943.2
chr16
72665123
72822781
+
AC026362.1
chr12
122975320
122982907
+
AC067930.1
chr8
143579636
143580670
+
AC079781.5
chr7
97851688
97972985
-
AC103746.1
chr15
96342953
96345651
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.