Entry Detail


General Information

Database ID:exR0719260
RNA Name:PTBP1
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):797075End Site(bp):812327
External Links:ENSG00000011304



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
ABCF1
chr6
30571393
30597179
+
ABLIM1
chr10
114431113
114768061
-
AC005943.1
chr19
1578339
1605445
-
AC010132.3
chr7
42909273
42932174
-
AC010422.3
chr19
12643831
12648397
-
AC073508.2
chr17
40627356
40665141
-
AC135050.2
chr16
31083439
31094956
-
AC138811.2
chr16
18788063
18801519
-
ACBD3
chr1
226144679
226186741
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADAMTS8
chr11
130404923
130428609
-
ADNP2
chr18
80109262
80147523
+
AHCY
chr20
34280268
34311802
-
AHCYL1
chr1
109984765
110023742
+
AHDC1
chr1
27534035
27604431
-
AHR
chr7
16916359
17346152
+
AL136454.1
chr1
192716132
192716653
+
AL136531.2
chr20
1317571
1393096
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-147a
chr9
120244985
120245004
-
hsa-miR-206
chr6
52144401
52144422
+
hsa-miR-4523
chr17
29390668
29390688
+
hsa-miR-4745-3p
chr19
804977
804999
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020928.2
chr19
36773712
36775908
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.