Entry Detail


General Information

Database ID:exR0719299
RNA Name:PTMA
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):231706895End Site(bp):231713541
External Links:ENSG00000187514



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC131160.1
chr3
183815568
183884889
-
AL590764.2
chrX
71103987
71111575
-
ACTR2
chr2
65227753
65271253
+
AC006030.1
chr2
74211604
74363377
-
AC008763.3
chr19
7678501
7682854
+
AC120057.2
chr17
7240427
7244635
-
AC092647.5
chr7
55887277
55955239
+
ABHD5
chr3
43690108
43734371
+
ADRA2C
chr4
3766348
3768526
+
ABT1
chr6
26596953
26600739
+
ADNP2
chr18
80109262
80147523
+
AC139530.2
chr17
81703371
81720539
+
AL358113.1
chr9
69035747
69255187
+
AC068946.1
chr2
219075329
219170827
-
AKAP8L
chr19
15380050
15419141
-
AL603832.3
chr1
112702614
112711433
-
ACAA2
chr18
49782164
49813953
-
ALDH18A1
chr10
95605941
95656711
-
AC009690.1
chr15
72284727
72375981
-
AL136454.1
chr1
192716132
192716653
+
ACTR1B
chr2
97655939
97664044
-
AGO1
chr1
35869808
35930532
+
ADGRA3
chr4
22345071
22516066
-
ADAM17
chr2
9488486
9556732
-
ABCF3
chr3
184186023
184194012
+
AC093323.1
chr4
6663396
6676755
+
AKR1A1
chr1
45550543
45570049
+
ADO
chr10
62804720
62808479
+
AC068547.1
chr2
151802651
151973949
-
ABL2
chr1
179099330
179229684
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-483-5p
chr11
2134181
2134202
-
hsa-miR-25-5p
chr7
100093610
100093630
-
hsa-miR-1244
chr2
231713368
231713393
+
hsa-miR-3652
chr12
103930425
103930442
+
hsa-miR-3960
chr9
127785879
127785898
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005083.1
chr7
20217577
20221700
+
AC007743.1
chr2
56173534
56185870
-
AC007952.4
chr17
19112000
19112636
-
AC008771.1
chr5
80411231
80488095
-
AC009022.1
chr16
69976297
70065948
-
AC012485.1
chr2
238231684
238255633
+
AC012615.1
chr19
1874871
1876169
-
AC016876.2
chr17
7581964
7584086
-
AC018521.1
chr17
47945424
47981736
+
AC026362.1
chr12
122975320
122982907
+
AC061975.1
chr17
28263634
28266369
-
AC068473.5
chr18
79677287
79679358
-
AC092755.2
chr15
59688517
59689418
+
AC116407.1
chr17
32141226
32143135
-
AC245033.4
chr15
82533175
82540008
-
AL121992.1
chr1
15586136
15603626
-
AL137003.1
chr6
16764346
16766883
+
AL137782.1
chr13
75549773
75807120
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.