Entry Detail


General Information

Database ID:exR0719407
RNA Name:RAB10
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):26034084End Site(bp):26137454
External Links:ENSG00000084733



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCE1
chr4
145098288
145129524
+
AC073508.2
chr17
40627356
40665141
-
AC245033.1
chr15
82536788
82573194
-
ACTB
chr7
5527148
5563784
-
ACTG2
chr2
73892314
73919865
+
AIMP2
chr7
6009255
6023834
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-330-3p
chr19
45639009
45639031
-
hsa-miR-574-5p
chr4
38868056
38868078
+
hsa-miR-654-3p
chr14
101040269
101040290
+
hsa-miR-1244
chr2
231713368
231713393
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009264.1
chr7
136685559
137182107
-
AC093591.2
chr4
127840198
127844040
-
AC245014.3
chr1
145281116
145281462
+
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.