Entry Detail


General Information

Database ID:exR0719423
RNA Name:RAB1B
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):66268590End Site(bp):66277492
External Links:ENSG00000174903



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD16A
chr6
31686955
31703356
-
ABTB2
chr11
34150987
34358010
-
AC010422.3
chr19
12643831
12648397
-
AC020909.1
chr19
50415799
50428409
+
ACAT2
chr6
159762045
159779112
+
ACTN4
chr19
38647649
38731589
+
ACTR5
chr20
38748460
38772520
+
ADAM19
chr5
157395534
157575775
-
AICDA
chr12
8602170
8612867
-
AK2
chr1
33007940
33080996
-
AKR1A1
chr1
45550543
45570049
+
AL121594.1
chr14
35122549
35317474
+
AL136295.5
chr14
24147548
24166452
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-122-5p
chr18
58451088
58451109
+
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC023509.1
chr12
53441741
53467528
+
AC079807.1
chr2
47905678
47907810
+
AC106886.2
chr16
30740667
30751381
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.