Entry Detail


General Information

Database ID:exR0719529
RNA Name:RALY
RNA Type:mRNA
Chromosome:chr20
Starnd:+
Coordinate:
Start Site(bp):33993646End Site(bp):34108308
External Links:ENSG00000125970



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
AC004922.1
chr7
99325879
99394653
+
AC008763.3
chr19
7678501
7682854
+
AC010422.3
chr19
12643831
12648397
-
AC245033.1
chr15
82536788
82573194
-
ACTB
chr7
5527148
5563784
-
ADA
chr20
44619522
44652233
-
AFDN
chr6
167826922
167972023
+
AGAP3
chr7
151085831
151144436
+
AGPAT4
chr6
161129967
161274061
-
AK2
chr1
33007940
33080996
-
AL031708.1
chr16
1632259
1686715
+
AL136295.4
chr14
24180395
24190416
-
AL162417.1
chr9
133098121
133163914
-
ALDH9A1
chr1
165662216
165698863
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-367-3p
chr4
112647877
112647898
-
hsa-miR-1181
chr19
10403505
10403525
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002116.1
chr19
36008638
36014235
-
AL022311.1
chr22
37876148
37895563
+
AL121992.1
chr1
15586136
15603626
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.