Entry Detail


General Information

Database ID:exR0719533
RNA Name:RAN
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):130872037End Site(bp):130877678
External Links:ENSG00000132341



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABT1
chr6
26596953
26600739
+
AC004997.1
chr22
30285238
30299482
-
AC006030.1
chr2
74211604
74363377
-
AC010132.3
chr7
42909273
42932174
-
AC092073.1
chr19
34396315
34409364
+
AC124312.1
chr15
24955034
25000276
+
AC135050.2
chr16
31083439
31094956
-
ACAA2
chr18
49782164
49813953
-
ACADVL
chr17
7217125
7225266
+
ACIN1
chr14
23058564
23095614
-
ACO1
chr9
32384603
32454769
+
ACO2
chr22
41469117
41528989
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR5
chr20
38748460
38772520
+
ADAT3
chr19
1905399
1913447
+
ADCY3
chr2
24819169
24919839
-
ADGRG1
chr16
57610652
57665580
+
ADH5
chr4
99070978
99088801
-
ADSL
chr22
40346500
40390463
+
AEN
chr15
88621337
88632281
+
AFDN
chr6
167826922
167972023
+
AGO3
chr1
35930718
36072500
+
AGPAT3
chr21
43865223
43987592
+
AIF1L
chr9
131096476
131123152
+
AKAP1
chr17
57085092
57121346
+
AKIRIN1
chr1
38991276
39006059
+
AL021546.1
chr12
120438198
120460006
+
AL022238.4
chr22
40346529
40410054
+
AL136295.4
chr14
24180395
24190416
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-302a-5p
chr4
112648224
112648246
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012236.1
chr15
31221999
31230838
-
AC079781.5
chr7
97851688
97972985
-
AC106864.1
chr4
112693047
112706810
-
AC113189.4
chr17
7439506
7445966
+
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.