Entry Detail


General Information

Database ID:exR0719623
RNA Name:RBM15B
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):51391285End Site(bp):51397908
External Links:ENSG00000259956



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCA2
chr9
137007234
137028922
-
AC010422.5
chr19
12664828
12669397
-
AC027644.4
chr7
66628958
66811189
+
AC138811.2
chr16
18788063
18801519
-
AC139530.2
chr17
81703371
81720539
+
ACAD10
chr12
111686056
111757107
+
ACOT7
chr1
6264269
6394391
-
ADGRL1
chr19
14147743
14206187
-
AHCY
chr20
34280268
34311802
-
AL669918.1
chr6
32813767
32838822
-
ALAS1
chr3
52198086
52214327
+
ALDH4A1
chr1
18871430
18902724
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4709-3p
chr14
74480135
74480157
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010542.4
chr16
66549280
66551189
+
AC027644.3
chr7
66739829
66740385
-
AC067930.1
chr8
143579636
143580670
+
AC100861.1
chr8
23224471
23230926
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.