exRNAdisease

Entry Detail

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General Information

Database ID: exR0719762 RNA Name: RFX1 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 13961530 End Site(bp): 14007039 External Links: ENSG00000132005

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE36936 Description: Gene Expression in the Human Mammary Epithelium during Initiation of Lactation. Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Day 42 post delivery Control Sample: 6h post delivery Number of Case: 7 Number of Control: 7 Number of Samples: 14

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC068580.4 chr11 1734821 1763954 - AC245033.1 chr15 82536788 82573194 - ACVR1B chr12 51951699 51997078 + ADARB1 chr21 45073853 45226560 + AIFM1 chrX 130129362 130165887 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-19a-3p chr13 91350939 91350961 + hsa-miR-19b-3p chr13 91351245 91351267 + hsa-miR-32-5p chr9 109046272 109046293 - hsa-miR-296-5p chr20 58817661 58817681 - hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-491-5p chr9 20716120 20716141 + hsa-miR-671-5p chr7 151238449 151238471 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22649065 Title: Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans Author: Mohammad MA, Hadsell DL, Haymond MW. Journal: Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76. Description: We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.