Entry Detail


General Information

Database ID:exR0720035
RNA Name:RPL27
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):42998273End Site(bp):43002959
External Links:ENSG00000131469



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAAS
chr12
53307456
53324864
-
AAGAB
chr15
67200667
67255195
-
AARSD1
chr17
42950526
42964498
-
AC010422.3
chr19
12643831
12648397
-
AC018523.2
chr11
14493783
14520344
-
AC025165.3
chr12
57772660
57797554
+
AC092073.1
chr19
34396315
34409364
+
AC093525.2
chr16
2496032
2520218
+
AC138811.2
chr16
18788063
18801519
-
AC245033.1
chr15
82536788
82573194
-
ACADM
chr1
75724347
75787575
+
ACO1
chr9
32384603
32454769
+
ACOT11
chr1
54542257
54639192
+
ACSS1
chr20
25006230
25058980
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR2
chr2
65227753
65271253
+
ACVR2B
chr3
38453890
38493142
+
ADM5
chr19
49688664
49690575
+
AFTPH
chr2
64524305
64593005
+
AIF1L
chr9
131096476
131123152
+
AIMP1
chr4
106315544
106349456
+
AKAP10
chr17
19904302
19978343
-
AL121594.1
chr14
35122549
35317474
+
AL358113.1
chr9
69035747
69255187
+
AL365205.1
chr6
41780349
41790141
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-142-3p
chr17
58331245
58331267
-
hsa-miR-302d-3p
chr4
112648006
112648028
-
hsa-miR-4485-3p
chr11
10508277
10508296
-
hsa-miR-7705
chr8
100703002
100703024
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC007952.4
chr17
19112000
19112636
-
AC016027.1
chr22
18076527
18078884
-
AC020663.1
chr16
4730115
4752565
-
AC026362.1
chr12
122975320
122982907
+
AC084082.1
chr8
66112667
66126632
+
AC108134.2
chr16
3156736
3157483
-
AC245033.4
chr15
82533175
82540008
-
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.