Entry Detail


General Information

Database ID:exR0720037
RNA Name:RPL28
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):55385345End Site(bp):55403250
External Links:ENSG00000108107



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCD3
chr1
94418389
94518666
+
AC004832.3
chr22
30409255
30428990
+
AC004922.1
chr7
99325879
99394653
+
AC005258.1
chr19
2269525
2341172
+
AC006064.6
chr12
6556886
6607367
-
AC010323.1
chr19
8308283
8321379
-
AC010422.3
chr19
12643831
12648397
-
AC024592.3
chr19
5866171
5903787
-
AC073508.2
chr17
40627356
40665141
-
AC093525.2
chr16
2496032
2520218
+
AC104389.5
chr11
5254392
5678434
-
AC138811.2
chr16
18788063
18801519
-
ACAT2
chr6
159762045
159779112
+
ACLY
chr17
41866917
41930542
-
ACO2
chr22
41469117
41528989
+
ACTA1
chr1
229431245
229434098
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADGRL1
chr19
14147743
14206187
-
AEBP2
chr12
19404045
19720801
+
AGRN
chr1
1020120
1056118
+
AHCY
chr20
34280268
34311802
-
AKAP13
chr15
85380571
85749358
+
AL049629.2
chr11
33698261
33722467
-
AL669918.1
chr6
32813767
32838822
-
ALAS1
chr3
52198086
52214327
+
ALDH2
chr12
111766887
111817532
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-6805-5p
chr19
55388186
55388207
+
hsa-miR-6805-3p
chr19
55388220
55388242
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC010327.5
chr19
55216660
55221616
+
AC012360.3
chr2
105334027
105337475
-
AC016747.1
chr2
61141592
61144969
-
AC020928.2
chr19
36773712
36775908
-
AC026362.1
chr12
122975320
122982907
+
AC026471.1
chr16
31456711
31459736
-
AC091564.7
chr11
6610883
6616594
-
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.