Entry Detail


General Information

Database ID:exR0720055
RNA Name:RPL4
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):66498015End Site(bp):66524532
External Links:ENSG00000174444



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AIF1L
chr9
131096476
131123152
+
ADD1
chr4
2843857
2930076
+
AL049629.2
chr11
33698261
33722467
-
AL133352.1
chr10
100505628
100529881
-
AASDHPPT
chr11
106075501
106098699
+
AC004223.3
chr17
35011349
35121493
-
ABT1
chr6
26596953
26600739
+
ADSL
chr22
40346500
40390463
+
AC245033.1
chr15
82536788
82573194
-
AC013394.1
chr15
92883413
92949230
+
AC008982.1
chr19
38817471
38840178
-
AC003002.3
chr19
57389884
57419994
+
ACTN4
chr19
38647649
38731589
+
ADD2
chr2
70607618
70768225
-
ADGRL2
chr1
81306160
81992436
+
AC004922.1
chr7
99325879
99394653
+
AC120057.2
chr17
7240427
7244635
-
ALAD
chr9
113386312
113401290
-
ACTC1
chr15
34790230
34795549
-
ADAR
chr1
154582057
154628013
-
AIMP1
chr4
106315544
106349456
+
ADCY3
chr2
24819169
24919839
-
AC015813.2
chr17
57989038
58007246
-
ABRACL
chr6
139028745
139043302
+
AD000671.2
chr19
35739252
35745432
-
ACP5
chr19
11574660
11579008
-
AGBL5
chr2
27042364
27070622
+
ABCC4
chr13
95019835
95301475
-
AC007192.1
chr19
18153158
18178117
+
AGAP2
chr12
57723761
57742157
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3654
chr7
133034860
133034878
-
hsa-miR-4745-5p
chr19
804941
804963
+
hsa-miR-6889-5p
chr22
41253023
41253045
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005899.4
chr17
32328441
32329395
+
AC007952.4
chr17
19112000
19112636
-
AC016026.1
chr22
17787652
17811497
-
AC016876.2
chr17
7581964
7584086
-
AC026362.1
chr12
122975320
122982907
+
AC051619.7
chr15
45200325
45200632
-
AC126365.1
chr17
20788071
20789584
+
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL117378.1
chr6
131901963
131920565
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.