Entry Detail


General Information

Database ID:exR0720057
RNA Name:RPL5
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):92832013End Site(bp):92841924
External Links:ENSG00000122406



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCB4
chr7
87401697
87480435
-
AC004922.1
chr7
99325879
99394653
+
AGTPBP1
chr9
85546539
85742029
-
ACO1
chr9
32384603
32454769
+
AL136454.1
chr1
192716132
192716653
+
ALDH18A1
chr10
95605941
95656711
-
ACTR3
chr2
113890063
113962596
+
ADSL
chr22
40346500
40390463
+
AC073896.1
chr12
56285916
56316059
-
AC015802.6
chr17
76563710
76570544
-
AC091167.2
chr15
90249556
90272208
+
AGK
chr7
141551278
141655244
+
ACIN1
chr14
23058564
23095614
-
AGO1
chr1
35869808
35930532
+
AASS
chr7
122073549
122144255
-
ABL1
chr9
130713016
130887675
+
AL022238.4
chr22
40346529
40410054
+
AL365273.2
chr10
95860548
95924844
+
ACP6
chr1
147629652
147670524
-
ACVR1B
chr12
51951699
51997078
+
ALDOA
chr16
30064164
30070457
+
ACTR2
chr2
65227753
65271253
+
AGA
chr4
177430774
177442437
-
AK2
chr1
33007940
33080996
-
AEN
chr15
88621337
88632281
+
ADNP2
chr18
80109262
80147523
+
AC073612.1
chr12
71674204
71698968
+
AL121594.1
chr14
35122549
35317474
+
ACTB
chr7
5527148
5563784
-
AGRN
chr1
1020120
1056118
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3654
chr7
133034860
133034878
-
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010163.1
chr10
78293842
78301003
+
AC018521.1
chr17
47945424
47981736
+
AC022167.2
chr16
8848105
8860456
+
AC024940.6
chr12
31280422
31280895
-
AC104461.1
chr1
200333193
200478669
+
AC132217.1
chr11
2129121
2129964
-
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.