Entry Detail


General Information

Database ID:exR0720065
RNA Name:RPLP1
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):69452814End Site(bp):69456205
External Links:ENSG00000137818



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC245033.1
chr15
82536788
82573194
-
ACOT9
chrX
23701055
23766475
-
AC004922.1
chr7
99325879
99394653
+
AFAP1L2
chr10
114294824
114404756
-
AGO3
chr1
35930718
36072500
+
ACTC1
chr15
34790230
34795549
-
AIG1
chr6
143060496
143341058
+
AGPAT1
chr6
32168212
32178096
-
ACTB
chr7
5527148
5563784
-
AHSA1
chr14
77457870
77469472
+
ADGRA3
chr4
22345071
22516066
-
ADRM1
chr20
62302093
62308862
+
AIFM1
chrX
130129362
130165887
-
ACADS
chr12
120725774
120740008
+
ABHD5
chr3
43690108
43734371
+
ADA
chr20
44619522
44652233
-
ACAA2
chr18
49782164
49813953
-
AC092143.1
chr16
89919165
89936092
+
AGPAT5
chr8
6708642
6761503
+
AL133352.1
chr10
100505628
100529881
-
AFF4
chr5
132875395
132963634
-
ADH5
chr4
99070978
99088801
-
AC023055.1
chr12
55757275
55827546
-
AC007192.1
chr19
18153158
18178117
+
AEBP2
chr12
19404045
19720801
+
AC118549.1
chr1
77562416
77683419
-
AC090517.4
chr15
56652488
56918571
-
AC010132.3
chr7
42909273
42932174
-
AGPAT3
chr21
43865223
43987592
+
AC010422.3
chr19
12643831
12648397
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-3917
chr1
25906384
25906403
-
hsa-miR-4426
chr1
192716333
192716349
+
hsa-miR-4707-5p
chr14
22956998
22957020
-
hsa-miR-4707-3p
chr14
22956957
22956978
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC004951.4
chr7
43951910
44019151
-
AC005618.1
chr5
141326210
141329357
+
AC007613.1
chr16
11741910
11744506
+
AC009403.1
chr7
155611231
155645205
-
AC009403.2
chr7
155474256
155644406
-
AC020928.2
chr19
36773712
36775908
-
AC022400.3
chr10
73674295
73730466
-
AC022400.5
chr10
73699151
73730487
-
AC060780.1
chr17
43148368
43171037
-
AC104793.1
chr4
161378953
161388417
+
AC245014.3
chr1
145281116
145281462
+
AL049795.2
chr1
32170733
32176568
+
AL117378.1
chr6
131901963
131920565
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.