Entry Detail


General Information

Database ID:exR0720066
RNA Name:RPLP2
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):809965End Site(bp):812880
External Links:ENSG00000177600



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010646.1
chr19
17235940
17255448
-
ALDOA
chr16
30064164
30070457
+
AL139300.1
chr14
103562962
103685924
+
AC011455.2
chr19
38915404
38949855
-
AGO4
chr1
35808016
35857890
+
AKAP1
chr17
57085092
57121346
+
AC007192.1
chr19
18153158
18178117
+
AC135050.2
chr16
31083439
31094956
-
ADGRL2
chr1
81306160
81992436
+
AC010422.3
chr19
12643831
12648397
-
AC020915.5
chr19
58228914
58315183
+
AKT2
chr19
40230317
40285536
-
AFTPH
chr2
64524305
64593005
+
ACIN1
chr14
23058564
23095614
-
AIFM1
chrX
130129362
130165887
-
AC004922.1
chr7
99325879
99394653
+
AL049629.2
chr11
33698261
33722467
-
ADCY1
chr7
45574140
45723116
+
ACTG1
chr17
81509971
81523847
-
AFDN
chr6
167826922
167972023
+
AC005258.1
chr19
2269525
2341172
+
ADRM1
chr20
62302093
62308862
+
AL121594.1
chr14
35122549
35317474
+
ALDH18A1
chr10
95605941
95656711
-
AGRN
chr1
1020120
1056118
+
ADH5
chr4
99070978
99088801
-
AACS
chr12
125065434
125143333
+
AGBL5
chr2
27042364
27070622
+
ABCF1
chr6
30571393
30597179
+
AC008878.3
chr19
7382834
7470241
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-7705
chr8
100703002
100703024
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007780.1
chr17
68413623
68524949
+
AC017104.1
chr2
231388976
231394991
+
AC018521.1
chr17
47945424
47981736
+
AC026362.1
chr12
122975320
122982907
+
AD000090.1
chr19
35557956
35581954
+
AL137782.1
chr13
75549773
75807120
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.