Entry Detail


General Information

Database ID:exR0720099
RNA Name:RPS27A
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):55231903End Site(bp):55235853
External Links:ENSG00000143947



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCF2
chr7
151207837
151227166
-
ABHD2
chr15
89087459
89202355
+
ABRACL
chr6
139028745
139043302
+
AC068946.1
chr2
219075329
219170827
-
AC091167.2
chr15
90249556
90272208
+
AC245033.1
chr15
82536788
82573194
-
ACAD8
chr11
134253495
134265855
+
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR2
chr2
65227753
65271253
+
ACVR1
chr2
157736444
157876330
-
ADAR
chr1
154582057
154628013
-
ADD1
chr4
2843857
2930076
+
ADORA2A
chr22
24417879
24442357
+
ADSL
chr22
40346500
40390463
+
AGAP1
chr2
235494043
236131800
+
AGPAT4
chr6
161129967
161274061
-
AGTPBP1
chr9
85546539
85742029
-
AHNAK
chr11
62433542
62556235
-
AIF1L
chr9
131096476
131123152
+
AL022238.4
chr22
40346529
40410054
+
AL133352.1
chr10
100505628
100529881
-
AL136454.1
chr1
192716132
192716653
+
AL139300.1
chr14
103562962
103685924
+
AL355315.1
chr10
97584374
97673910
+
ALDH7A1
chr5
126531200
126595362
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4426
chr1
192716333
192716349
+
hsa-miR-4485-3p
chr11
10508277
10508296
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC091564.7
chr11
6610883
6616594
-
AC104257.1
chr8
131308545
131317632
+
AC106864.1
chr4
112693047
112706810
-
AC239868.1
chr1
149861271
149862504
+
AC245033.4
chr15
82533175
82540008
-
AL031656.1
chr20
42685404
42688562
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.