Entry Detail


General Information

Database ID:exR0720123
RNA Name:RPSA
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):39406716End Site(bp):39412542
External Links:ENSG00000168028



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD12
chr20
25294742
25390835
-
ABHD2
chr15
89087459
89202355
+
AC008575.1
chr5
112827213
112867582
+
AC018523.2
chr11
14493783
14520344
-
AC104109.3
chr5
134167170
134226071
-
ACACA
chr17
37084992
37406836
-
ACSL6
chr5
131949973
132012243
-
ACTA2
chr10
88935074
88991339
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
AFF4
chr5
132875395
132963634
-
AGFG1
chr2
227472152
227561214
+
AHCY
chr20
34280268
34311802
-
AL355987.3
chr9
136791379
136800595
+
ALDH7A1
chr5
126531200
126595362
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC005618.1
chr5
141326210
141329357
+
AC005899.4
chr17
32328441
32329395
+
AC006064.5
chr12
6510275
6510522
+
AC016876.2
chr17
7581964
7584086
-
AC019205.1
chr6
73263212
73301789
+
AC023509.1
chr12
53441741
53467528
+
AC068205.2
chr11
43578889
43840030
+
AC087190.3
chr16
9104848
9113181
+
AC091564.7
chr11
6610883
6616594
-
AC124312.3
chr15
25087661
25088896
+
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.