Entry Detail


General Information

Database ID:exR0720179
RNA Name:RTN3
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):63681446End Site(bp):63759891
External Links:ENSG00000133318



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAGAB
chr15
67200667
67255195
-
ABCA3
chr16
2275881
2340746
-
AC007192.1
chr19
18153158
18178117
+
AC034102.2
chr12
56101331
56109289
+
AC068946.2
chr2
219209772
219222738
-
AC073508.2
chr17
40627356
40665141
-
AC093525.1
chr16
2513965
2527955
+
AC110275.1
chr8
43018424
43077334
+
AC245033.1
chr15
82536788
82573194
-
ACBD5
chr10
27195214
27242130
-
ACTR2
chr2
65227753
65271253
+
ADGRG6
chr6
142301854
142446266
+
AGK
chr7
141551278
141655244
+
AHCTF1
chr1
246839098
246931967
-
AKR1B1
chr7
134442356
134459284
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005332.5
chr17
68133201
68135935
+
AC104461.1
chr1
200333193
200478669
+
AC125807.2
chr12
3041437
3044950
+
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.