Entry Detail



General Information

Database ID:exR0720264
RNA Name:SAMD4B
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):39342396End Site(bp):39385710
External Links:ENSG00000179134



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABT1
chr6
26596953
26600739
+
AC008878.3
chr19
7382834
7470241
+
AC010422.3
chr19
12643831
12648397
-
ACOT7
chr1
6264269
6394391
-
ACOT8
chr20
45841721
45857405
-
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
ADNP2
chr18
80109262
80147523
+
AGO1
chr1
35869808
35930532
+
AHCY
chr20
34280268
34311802
-
AHSA1
chr14
77457870
77469472
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-299-3p
chr14
101023832
101023853
+
hsa-miR-491-5p
chr9
20716120
20716141
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-671-5p
chr7
151238449
151238471
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-1224-5p
chr3
184241405
184241423
+
hsa-miR-1321
chrX
85835832
85835849
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002116.1
chr19
36008638
36014235
-
AC239868.1
chr1
149861271
149862504
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.