exRNAdisease

Entry Detail

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General Information

Database ID: exR0720301 RNA Name: SCAMP2 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 74843730 End Site(bp): 74873365 External Links: ENSG00000140497

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE36936 Description: Gene Expression in the Human Mammary Epithelium during Initiation of Lactation. Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Day 42 post delivery Control Sample: 6h post delivery Number of Case: 7 Number of Control: 7 Number of Samples: 14

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABR chr17 1003518 1229738 - AC068580.4 chr11 1734821 1763954 - AC092073.1 chr19 34396315 34409364 + AC138811.2 chr16 18788063 18801519 - AC245033.1 chr15 82536788 82573194 - ACADVL chr17 7217125 7225266 + ACTB chr7 5527148 5563784 - AGPAT3 chr21 43865223 43987592 + ALDH18A1 chr10 95605941 95656711 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-17-5p chr13 91350618 91350640 + hsa-miR-20a-5p chr13 91351072 91351094 + hsa-miR-106a-5p chrX 134170244 134170266 - hsa-miR-124-3p chr8 64379210 64379231 + hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-106b-5p chr7 100094043 100094063 - hsa-miR-302a-3p chr4 112648186 112648208 - hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-373-3p chr19 53788748 53788770 + hsa-miR-520e-3p chr19 53675764 53675784 + hsa-miR-519b-3p chr19 53695263 53695284 + hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-423-5p chr17 30117095 30117117 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026471.1 chr16 31456711 31459736 - AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22649065 Title: Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans Author: Mohammad MA, Hadsell DL, Haymond MW. Journal: Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76. Description: We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.