Entry Detail


General Information

Database ID:exR0720314
RNA Name:SCD
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):100347233End Site(bp):100364826
External Links:ENSG00000099194



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010132.3
chr7
42909273
42932174
-
AC018523.2
chr11
14493783
14520344
-
AC048338.1
chr12
122207779
122266423
-
AC092143.1
chr16
89919165
89936092
+
AC120057.2
chr17
7240427
7244635
-
AC138811.2
chr16
18788063
18801519
-
ACP1
chr2
264140
278283
+
ACP6
chr1
147629652
147670524
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR2
chr2
65227753
65271253
+
ADAR
chr1
154582057
154628013
-
ADSL
chr22
40346500
40390463
+
AEBP2
chr12
19404045
19720801
+
AGBL5
chr2
27042364
27070622
+
AGPS
chr2
177392757
177559299
+
AIG1
chr6
143060496
143341058
+
AKIRIN2
chr6
87674860
87702233
-
AL022238.4
chr22
40346529
40410054
+
ALDH7A1
chr5
126531200
126595362
-
ALDH9A1
chr1
165662216
165698863
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-7-5p
chr19
4770700
4770723
+
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-1321
chrX
85835832
85835849
+
hsa-miR-1197
chr14
101025620
101025640
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004816.1
chr14
70809841
70815994
+
AC005618.1
chr5
141326210
141329357
+
AC009446.1
chr8
71675300
71702786
+
AC010719.1
chr7
25948657
25949403
-
AC106795.2
chr5
177950335
177963960
+
AC106864.1
chr4
112693047
112706810
-
AC124068.2
chr15
89335053
89336161
+
AC124283.3
chr17
82578023
82578616
+
AC126365.1
chr17
20788071
20789584
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.