Entry Detail


General Information

Database ID:exR0720396
RNA Name:SEC11A
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):84669538End Site(bp):84716460
External Links:ENSG00000140612



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCA1
chr9
104781006
104928155
-
AC007192.1
chr19
18153158
18178117
+
AC008982.1
chr19
38817471
38840178
-
AC245033.1
chr15
82536788
82573194
-
ACADM
chr1
75724347
75787575
+
ACIN1
chr14
23058564
23095614
-
ACTA1
chr1
229431245
229434098
-
ACTG1
chr17
81509971
81523847
-
ACTN1
chr14
68874143
68979440
-
ADGRL1
chr19
14147743
14206187
-
ADH5
chr4
99070978
99088801
-
AHCYL1
chr1
109984765
110023742
+
AL121753.1
chr20
35267885
35280043
-
AL136295.4
chr14
24180395
24190416
-
AL136454.1
chr1
192716132
192716653
+
AL365205.1
chr6
41780349
41790141
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020978.7
chr16
68224713
68227734
+
AC106864.1
chr4
112693047
112706810
-
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.