Entry Detail


General Information

Database ID:exR0720470
RNA Name:SERF2
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):43777087End Site(bp):43802589
External Links:ENSG00000140264



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
ABCB4
chr7
87401697
87480435
-
AC005258.1
chr19
2269525
2341172
+
AC005943.1
chr19
1578339
1605445
-
AC023055.1
chr12
55757275
55827546
-
AC073896.1
chr12
56285916
56316059
-
AC099811.2
chr17
42119674
42154916
-
AC120057.2
chr17
7240427
7244635
-
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTC1
chr15
34790230
34795549
-
ACTG1
chr17
81509971
81523847
-
ACTR8
chr3
53867066
53882152
-
ADA
chr20
44619522
44652233
-
ADD3
chr10
109996368
110135565
+
ADIPOR1
chr1
202940826
202958572
-
AGAP4
chr10
45825594
45853875
-
AHCY
chr20
34280268
34311802
-
AL049629.2
chr11
33698261
33722467
-
AL121753.1
chr20
35267885
35280043
-
AL136295.1
chr14
24189157
24213473
-
AL136295.4
chr14
24180395
24190416
-
AL139260.3
chr1
38864501
38881617
-
ALDH18A1
chr10
95605941
95656711
-
ALDH4A1
chr1
18871430
18902724
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-31-5p
chr9
21512158
21512178
-
hsa-miR-296-3p
chr20
58817626
58817647
-
hsa-miR-423-5p
chr17
30117095
30117117
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005618.1
chr5
141326210
141329357
+
AC016876.2
chr17
7581964
7584086
-
AC126365.1
chr17
20788071
20789584
+
AL121603.2
chr14
34874343
34876459
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.