Entry Detail


General Information

Database ID:exR0720516
RNA Name:SET
RNA Type:mRNA
Chromosome:chr9
Starnd:+
Coordinate:
Start Site(bp):128683424End Site(bp):128696400
External Links:ENSG00000119335



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
ABCB8
chr7
151028422
151047782
+
ABCC6
chr16
16148928
16223522
-
AC007846.2
chr17
5772926
6080792
+
AC010463.1
chr19
17267418
17282966
+
AC012254.2
chr18
47108188
47176345
-
AC138811.2
chr16
18788063
18801519
-
ACACA
chr17
37084992
37406836
-
ACBD3
chr1
226144679
226186741
-
ACTB
chr7
5527148
5563784
-
ACTN4
chr19
38647649
38731589
+
ADM
chr11
10305073
10307397
+
AGO3
chr1
35930718
36072500
+
AHCYL1
chr1
109984765
110023742
+
AKAP12
chr6
151239967
151358559
+
AL139011.2
chr1
160216800
160285130
-
AL590132.1
chr1
210858125
211134146
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3648
chr21
8987026
8987046
+
hsa-miR-6728-3p
chr1
8866502
8866522
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC124068.2
chr15
89335053
89336161
+
AL121985.1
chr1
160670778
160699761
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.