Entry Detail


General Information

Database ID:exR0720533
RNA Name:SF1
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):64764606End Site(bp):64778786
External Links:ENSG00000168066



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
AC005258.1
chr19
2269525
2341172
+
AC008750.8
chr19
51350373
51368099
-
AC008878.3
chr19
7382834
7470241
+
AC011005.1
chr7
129126518
129130793
+
AC015813.2
chr17
57989038
58007246
-
AC245033.1
chr15
82536788
82573194
-
ACAD9
chr3
128879596
128916067
+
ACTB
chr7
5527148
5563784
-
ACTR2
chr2
65227753
65271253
+
AKR1B1
chr7
134442356
134459284
-
AL031708.1
chr16
1632259
1686715
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC012321.1
chr16
69703065
69704652
+
AC022336.2
chr3
124723788
124726325
+
AD000090.1
chr19
35557956
35581954
+
AL121992.1
chr1
15586136
15603626
-
AL137127.1
chr1
19072110
19075511
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.