Entry Detail


General Information

Database ID:exR0720545
RNA Name:SFPQ
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):35176378End Site(bp):35193145
External Links:ENSG00000116560



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAAS
chr12
53307456
53324864
-
ABLIM1
chr10
114431113
114768061
-
AC008982.1
chr19
38817471
38840178
-
AC010422.3
chr19
12643831
12648397
-
AC091551.1
chr18
50968019
51058144
+
AC105052.3
chr7
102637049
102671641
-
AC118553.2
chr1
99970011
100083321
+
ACSS1
chr20
25006230
25058980
-
ACTR2
chr2
65227753
65271253
+
ADAMTSL4
chr1
150549369
150560937
+
ADGRA3
chr4
22345071
22516066
-
ADORA2A
chr22
24417879
24442357
+
AGO4
chr1
35808016
35857890
+
AHCY
chr20
34280268
34311802
-
AKR1A1
chr1
45550543
45570049
+
AL117339.5
chr10
38094368
38360098
+
AL136295.5
chr14
24147548
24166452
+
AL365205.1
chr6
41780349
41790141
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-205-5p
chr1
209432166
209432187
+
hsa-miR-3652
chr12
103930425
103930442
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006504.5
chr19
27793431
27984984
+
AC067930.1
chr8
143579636
143580670
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.