Entry Detail


General Information

Database ID:exR0720823
RNA Name:SLC25A3
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):98593591End Site(bp):98606379
External Links:ENSG00000075415



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD17A
chr19
1876810
1885547
-
ABT1
chr6
26596953
26600739
+
AC023055.1
chr12
55757275
55827546
-
AC091167.2
chr15
90249556
90272208
+
AC092835.1
chr2
95207535
95259774
+
AC093525.2
chr16
2496032
2520218
+
AC245033.1
chr15
82536788
82573194
-
ACTA1
chr1
229431245
229434098
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTG2
chr2
73892314
73919865
+
ACTR2
chr2
65227753
65271253
+
ACY1
chr3
51983340
51989197
+
ADIPOR1
chr1
202940826
202958572
-
AHCY
chr20
34280268
34311802
-
AICDA
chr12
8602170
8612867
-
AKAP12
chr6
151239967
151358559
+
AKIRIN1
chr1
38991276
39006059
+
AL117348.2
chr1
225886696
225924278
-
AL355315.1
chr10
97584374
97673910
+
AL355987.1
chr9
136738167
136748453
-
AL358113.1
chr9
69035747
69255187
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-205-5p
chr1
209432166
209432187
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007406.5
chr12
273954
277123
-
AC087239.1
chr12
25385670
25386241
-
AC106886.2
chr16
30740667
30751381
+
AC245014.3
chr1
145281116
145281462
+
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.