Entry Detail


General Information

Database ID:exR0720917
RNA Name:SLC38A1
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):46183063End Site(bp):46270017
External Links:ENSG00000111371



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009133.6
chr16
29812261
29820092
+
AC018523.2
chr11
14493783
14520344
-
AC090004.1
chr3
14135217
14148252
+
AC091959.3
chr5
146203550
146339251
+
AC093525.2
chr16
2496032
2520218
+
ACADM
chr1
75724347
75787575
+
ADAM19
chr5
157395534
157575775
-
ADAMTS19
chr5
129460281
129738683
+
ADGRV1
chr5
90529344
91164437
+
ADH5
chr4
99070978
99088801
-
AKIRIN1
chr1
38991276
39006059
+
AKT2
chr19
40230317
40285536
-
AL121594.1
chr14
35122549
35317474
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002310.1
chr16
30534752
30537149
+
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.