Entry Detail



General Information

Database ID:exR0721008
RNA Name:SLC7A5
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):87830023End Site(bp):87869507
External Links:ENSG00000103257



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
AC010422.3
chr19
12643831
12648397
-
AC018523.2
chr11
14493783
14520344
-
ACAP3
chr1
1292390
1309609
-
ACTB
chr7
5527148
5563784
-
ACTN4
chr19
38647649
38731589
+
ACTR3
chr2
113890063
113962596
+
ADAM8
chr10
133262420
133276868
-
ADPRHL2
chr1
36088892
36093932
+
AKIRIN1
chr1
38991276
39006059
+
AKTIP
chr16
53491040
53504411
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-199a-5p
chr1
172144592
172144614
-
hsa-miR-199b-5p
chr9
128244783
128244805
-
hsa-miR-130a-3p
chr11
57641252
57641273
+
hsa-miR-301a-3p
chr17
59151149
59151171
-
hsa-miR-130b-3p
chr22
21653354
21653375
+
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-6775-3p
chr16
87834592
87834612
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005618.1
chr5
141326210
141329357
+
AC012236.1
chr15
31221999
31230838
-
AC016876.2
chr17
7581964
7584086
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.