Entry Detail


General Information

Database ID:exR0721078
RNA Name:SMC1A
RNA Type:mRNA
Chromosome:chrX
Starnd:-
Coordinate:
Start Site(bp):53374149End Site(bp):53422728
External Links:ENSG00000072501



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007192.1
chr19
18153158
18178117
+
AC010646.1
chr19
17235940
17255448
-
AC040162.1
chr16
67929614
67936017
-
ACTB
chr7
5527148
5563784
-
ACTN1
chr14
68874143
68979440
-
AD000671.1
chr19
35745678
35754519
+
ADIPOR1
chr1
202940826
202958572
-
AFDN
chr6
167826922
167972023
+
AGAP6
chr10
49982190
50010499
+
AHCY
chr20
34280268
34311802
-
AL162417.1
chr9
133098121
133163914
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-92a-3p
chrX
134169544
134169565
-
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-34c-5p
chr11
111513451
111513473
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC124068.2
chr15
89335053
89336161
+
AD000090.1
chr19
35557956
35581954
+
AL035458.2
chr20
34234840
34281173
-
AL135925.1
chr10
79825902
79827602
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.