Entry Detail



General Information

Database ID:exR0721135
RNA Name:SND1
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):127652194End Site(bp):128092609
External Links:ENSG00000197157



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

Created with Highcharts 7.0.1Expression value (z-scores)Chart context menuExpression boxplotCaseControl1.21.31.41.51.61.71.81.9
GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCA1
chr9
104781006
104928155
-
ABCF2
chr7
151207837
151227166
-
AC005943.1
chr19
1578339
1605445
-
AC010422.3
chr19
12643831
12648397
-
AC011462.1
chr19
41350853
41425001
+
AC020915.5
chr19
58228914
58315183
+
AC073610.2
chr12
48903503
48957365
-
AC092143.1
chr16
89919165
89936092
+
AC124312.1
chr15
24955034
25000276
+
AC245033.1
chr15
82536788
82573194
-
ACTB
chr7
5527148
5563784
-
ACTR1B
chr2
97655939
97664044
-
ACTR2
chr2
65227753
65271253
+
ADRM1
chr20
62302093
62308862
+
ADSL
chr22
40346500
40390463
+
AGO1
chr1
35869808
35930532
+
AGTRAP
chr1
11736084
11754802
+
AHCY
chr20
34280268
34311802
-
AL022238.4
chr22
40346529
40410054
+
AL031708.1
chr16
1632259
1686715
+
AL365205.1
chr6
41780349
41790141
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-18a-5p
chr13
91350756
91350778
+
hsa-miR-302b-3p
chr4
112648489
112648511
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
AL049795.2
chr1
32170733
32176568
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.



 
AL049795.2